One of the most famous depictions of ancient manipulation is seen in this 4th Century Votive relief of the pre-Hippopractic physician Asklepios.
 

The tablet portrays Asklepios the 'moderate practitioner' accompanied by "Hygeia", The Goddess of Health, performing a manipulation of the vertebral column. This marble sculpture was excavated from the entrance to the Asklipion Sanctuary in Pireas and is permanently exhibited in the museum of Pireas in Greece.

Dr. D.D. Palmer documented the significance of this relief to our profession in his book "The Chiropractor Adjuster". He calls specific attention to Asklipios and his teachings as the foundation for what he later developed and termed 'chiropractic', thus keeping its original Greek identity. He adds that the replacing of displaced vertebrae for the relief of humanity "rediscovered and known as chiropractic was also known and practiced by Asklipios and his followers 400 years before Christ". In ancient Greece in those days there were over 380 Asklipia Sanctuaries scattered throughout the land.

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